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To determine phenytoin concentration in the blood, to maintain an calcium and albumin for phenytoin appropriate level, and to detect phenytoin toxicity

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(5) Changes in albumin levels or the binding affinity of phenytoin to albumin must be taken into account (total phenytoin levels are of little .

Because calcium is a highly albumin-bound ion, changes in the albumin level . Phenytoin lowers calcium levels in the body by various mech-anisms. Careful .

Patient's calculated Creatinine Clearance < 20? Yes Phenytoin Level mg/L Serum Albumin g/dL . Calcium Correction for Hypoalbuminemia; Creatinine Clearance (Cockcroft .

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